Rimonabant is an anorectic anti obesity drug. It is a CB1 cannabinoid receptor antagonist. Its main avenue of effect is reduction in appetite. Obesity is now the most common nutritional disorder in western countries. Defined as a body mass index of greater than 30, it arises from the accumulation of excess fat in the body from overconsumption of fatty foods. Prevalence of obesity in the US and Europe has reached epidemic levels.
Data from the World Health Organization’s MONICA project show that in some parts of Europe over 70% of men aged 55-64 years are clinically obese or overweight (BMI >25) and almost 70% of women in this age group. One in five of all Americans is obese and one in three overweight. Furthermore, increasing rates of childhood obesity are likely to exacerbate the trend towards increasing obesity in adulthood.
Obesity is more than a cosmetic problem. Many serious medical conditions have been linked to obesity, including type 2 diabetes, heart disease, high blood pressure, and stroke. Obesity is also linked to higher rates of certain types of cancer. Men who are obese are more likely than nonobese men to develop cancer of the colon, rectum, or prostate. Women who are obese are more likely than nonobese women to develop cancer of the gallbladder, uterus, cervix, or ovaries. Esophageal cancer has also been associated with obesity.
Rimonabant works by blocking endogenous cannabinoid binding to neuronal CB1 receptors. Activation of these receptors by endoegenous cannabinoids, such as anadamide, increases appetite. It is the most advanced endocannabinoid receptor antagonist in clinical development and offers a novel therapeutic approach to appetite control and weight reduction. The drug also has potential as a treatment for smoking cessation because the endocannabinoid system is involved in the body’s response to tobacco dependence.
The doctor usually prescribes dose of 20 mg Rimonabant diet pill. Dosage of Rimonabant diet pill should be balanced with a low-calorie diet and regular exercises. Avoid over dose of the pill. You should strictly adhere to your doctor’s prescription to keep away from any future complications.
Usage of Rimonabant also includes a few side effects which diminish as one adjusts to the medication such as:
• Stomach upset
• Restlessness
• Lethargy or Sleepiness
• Fatigue
• Nausea
• Dizziness
• Depression
• Consumption of Acomplia dosage should be prevented if you are:
• Allergic to any of the ingredients of Acomplia
• Pregnant or breast-feeding a baby
Side effects listed above in most cases are minor and diminish in time. Results from the phase III trial program suggest Rimonabant is well tolerated in long-term use.
Tell your doctor if you have or had a medical record of impaired renal function, suffered from epilepsy, or impaired liver infection. It is also desirable to inform your doctor regarding any medications you are engaged in, to circumvent any contraindication of Rimonabant.
Before you go ahead with Rimonabant medication, prior conversation with your doctor is suggested to stay away from any future harmful repercussions. Seek instantaneous medical support, if you undergo these side effects for an extended phase of time or any other critical side effects.